Message: 3
Date: Mon, 24 Mar 2014 12:28:29 +0900
From: jh kim <jhkim.merrf@gmail.com>
Subject: Re: [Freesurfer] Difference in volumes btw 5.1 and 5,3
To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Message-ID:
<CADiwdtbtNUbiXaaQgoR9bwLBrEwFDfu4+Zv5VhViDhz3nfQOCg@mail.gmail.com>
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Dear Prof. Fischl
Thanks for the valuable comments.
Kim
2014-03-23 3:26 GMT+09:00 Bruce Fischl <fischl@nmr.mgh.harvard.edu>:
Hi Kim
we of course always strive to make things more accurate, but in the end
it will depend on the details of your acquisition and such. I don't think
I have a better answer than that, other than to say look at the
segmentations and see if you think they are more accurate in one case
than the other.
sorry
Bruce
On Sun, 23 Mar 2014, jh kim wrote:
Dear Prof. Fischl
Thanks for the prompt response.
The more specific reason of my query is that there was a difference in
statistical significance between two FS versions.
For example, the result of group comparison of left thalamic volumes
(ANCOVA
controlling for age and eICV) is statistically significant (p = 0.04)
when
using FS 5.1, whereas the result is no longer significant at all (p =
0.28)
in case of FS 5.3.
I'm a little confused about this discrepancy.
Which result should I trust?
Thank you in advance for your comments.
Kim
2014-03-23 2:59 GMT+09:00 Bruce Fischl <fischl@nmr.mgh.harvard.edu>:
Hi Kim
there are probably lots of little reasons for the differences.
This is
always true for different versions, and the reason we never mix
versions
cheers
Bruce
On
Sun, 23 Mar 2014, jh kim wrote:
Dear FS lists
When I measured subcortical GM volumes in the same subjects by
using both
version 5.1 and 5.3, I have observed a considerable difference
in volumes
between the two versions.
For instance, please see the left thalamic volumes below.
I cannot figure out why there is much difference between the
versions.
Which result is more reliable?
Left-Thalamus-Proper_5.3
Left-Thalamus-Proper_5.1
10313
9757
8924.8
7746
9834.8
8287
7935.2
7034
8764.1
7747
9411.8
8037
7636.7
8051
9334.7
8255
10024.3
8171
8757.7
6900
9540.9
8316
9294.4
8369
8091
7366
9103.7
7818
9310.2
7974
7583
6872
9838.9
8911
8829.6
8004
9094.8
6973
9492.3
8922
8821.6
7691
7971.6
7376
9901.2
8936
9773.9
8855
9283.7
7615
8801.6
7690
8505.1
7325
8981
7258
9644.7
8860
9104.2
8298
8494.8
7402
9024.9
7721
8117.8
7226
8001.8
7548
8392.3
7668
8606.6
8173
9126.7
7595
8093
7885
8317.7
7157
10556
9307
8669.6
8374
8034.7
7338
8148.5
7276
9048.1
8064
8160.1
7014
8747.9
7894
8329.9
6866
8415.8
8189
9246.9
8256
8194.1
7183
9629.2
9579
7688.2
6398
8349.2
8238
8366.2
7348
8436.5
7616
8372.3
6977
9396.4
7589
9327.5
7684
10001.8
8627
9762.4
9228
8841
8532
8342.4
8024
8645.7
7725
Any comment would be appreciated.
Thank you.
Kim
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