Hi Doug,

I reduced the total time points, however, I found the eff and VRF value all became smaller as the time points decreased, and I still got some null events more than 7s. If I set the time points as 470s, I got most 5-7 null events, except the last 35s null event, and then its eff is 0.007, and VRFAvg is 1.7. Compared with 500 time points (eff 0.01, VFRAvg 2.58), 470s is bad design. From one paper, I learned that exponential distribution produced less variance compared with unity distribution, and maybe optseq2 likes exponential distribution more, so can I use the 470s design without the last 35s null events? Is the value of eff and VFRAvg OK?


......
......
819.0000    5   13.000   1.0000       diamond
832.0000    0    5.000   1.0000          NULL
837.0000    2   13.000   1.0000          star
850.0000    0    5.000   1.0000          NULL
855.0000    2   13.000   1.0000          star
868.0000    0    5.000   1.0000          NULL
873.0000    3   14.000   1.0000          star
887.0000    0    6.000   1.0000          NULL
893.0000    4   12.000   1.0000       diamond
905.0000    0   35.000   1.0000          NULL



On Tue, Oct 20, 2009 at 11:59 AM, Douglas N Greve <greve@nmr.mgh.harvard.edu> wrote:
I think this is partially a bug in optseq and partially a problem with your design. You have a total amount of stimulation time = 12*9+13*8+14*8+12*9+13*8+14*8 = 648 sec. Your run lasts 500*2 = 1000 sec, so the total amount of fixation time is 1000-648 = 352 sec. You have 8*4+9*2 = 50 stimuli, so the average time between stimuli (ie, average null) will be 352/50 = 7.04s. Yet you have constrained optseq to give you nulls between 5 and 7 sec. You need to relax this constraint or reduce the total number of time points.

doug

杨宏宇 wrote:
Hi list,

I am using optseq2 to design my fMRI study. These are my scripts:

optseq2 --ntp 500 --tr 2 --psdwin 0 40 1 --ev star 12 9 --ev star 13 8 --ev star 14 8 --ev diamond 12 9 --ev diamond 13 8 --ev diamond 14 8 --tnullmin 5 --tnullmax 7 --nkeep 3 --o ex.event12.13.14s --nsearch 5000

I have 2 events, which last for 12,13, and 14s. I found that the schedule documents I got had many null events more than 7s, however, I have set the maximam as 7s. In the sum logfile, I found that my script was recorded correctly, so could you please tell me the reason, and how to solve the problem?

Many thanks,
Hongyu
Division on Addiction,
Psychiatry Department,
UT Southwestern Medical Center

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