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Hello,

I have a question regarding the way ROI-wise values are calculated using PETSurfer. 

We ran the PETSurfer pipeline with PVC=0 and noticed that a relatively small ROI like Putamen has one of the highest values of regional distribution of a PET tracer.  

Is it the case that the PETSurfer ROI-wise value outputs were averaged, or normalized by each ROI’s volume? And what measure was divided, GM volume, number of voxels, or something else? 

Thank you in advance!

Best regards,
Zhener

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