Your interpretation is right (ie, controls > patients for
red/yellow/orange). When you compared the two groups in your separate
analysis, did you control for age?
doug

On 06/24/2014 02:19 PM, Emma Thompson wrote:
> Hi Freesurfers,
> I am reposting this as my last email bounced.
>
> I have conducted a DODS analysis in qdec with group (controls vs
> patients) set as my fixed factor and age as a nuisance variable to
> determine if my groups differ in cortical thickness. Controls were
> added first in the .levels file followed by patients. When I view the
> results in the display window for "do controls differ from patients in
> cortical thickness" I see a significant cluster for the caudal
> anterior cingulate, denoted by a red-orange blob and a positive
> t-value. I'm wondering if this simply means that controls had greater
> cortical thickness compared to patients after controlling for age? The
> reason I ask is that I'm a little confused since when I created an ROI
> for this cluster using tksurfer and then extracted the means and sd, I
> see that the patients actually have larger means than the controls,
> the opposite of my interpretation of the results presented by the qdec
> display. Furthermore, if I extract the means and sds for the entire
> caudal anterior cingulate using the aparc file, I get means that are
> larger in controls, compared to patients, which seems consistent with
> qdec. Any ideas? Thanks for all the help.
>
>

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--
Douglas N. Greve, Ph.D.
MGH-NMR Center
greve@nmr.mgh.harvard.edu
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