Actually my input is not the difference map, but the separate time points (it's timepoint 2 weighted with -1 and timepoint 1 weighted with 1, described in the matrix file I sent you). So in order to determine whether there's thickening or thinning in the controls and training subjects, would I still need to use the additional contrasts [1 0 0 ....] and [0 1 0 ....]? Thank you.

On Thu, Oct 25, 2012 at 3:48 PM, Douglas N Greve <greve@nmr.mgh.harvard.edu> wrote:

And the input is already TimePoint2-TimePoint1? If so, then you will need two more contrasts: [1 0 0 ....] and [0 1 0 ....]. The first tells you if controls are thinning (blue) or thickening (red), the 2nd tells you if the training is doing the same.
doug

On 10/25/2012 03:34 PM, Ryan wrote:

Doug,
Yes, it's a longitudinal study since we MRI participants pre-training and post-training.

On Thu, Oct 25, 2012 at 2:37 PM, Douglas N Greve <greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>> wrote:

I'm not sure I understand. Is this a longitudinal study?

On 10/25/2012 01:26 PM, Ryan wrote:

Doug,
Also, how can I tell if it's thickening or thinning if
red/blue corresponds to the group? Thanks for the help.

---------- Forwarded message ----------
From: *Douglas N Greve* <greve@nmr.mgh.harvard.edu
<mailto:greve@nmr.mgh.harvard.edu>
<mailto:greve@nmr.mgh.harvard.edu
<mailto:greve@nmr.mgh.harvard.edu>>>
Date: Thu, Oct 25, 2012 at 12:20 PM
Subject: Re: Files
To: Ryan <wmcgarry@gmu.edu <mailto:wmcgarry@gmu.edu>
<mailto:wmcgarry@gmu.edu <mailto:wmcgarry@gmu.edu>>>

That contrast will compute training-controls. In the maps,
red/yellow will mean training>controls, blue/cyan otherwise

doug

On 10/25/2012 12:47 AM, Ryan wrote:

Doug,
Here are the Xg.dat (where the first column is for
controls and
the second column is for training subjects) and mtx files, I
didn't use the FSGD design. Please let me know if this is
sufficient for you to answer my question, thank you very much.

-- -Ryan

-- Douglas N. Greve, Ph.D.
MGH-NMR Center
greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>
<mailto:greve@nmr.mgh.harvard.edu

<mailto:greve@nmr.mgh.harvard.edu>>
Phone Number: 617-724-2358 <tel:617-724-2358>
<tel:617-724-2358 <tel:617-724-2358>>
Fax: 617-726-7422 <tel:617-726-7422> <tel:617-726-7422

<tel:617-726-7422>>

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-- Douglas N. Greve, Ph.D.
MGH-NMR Center
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--
-Ryan

--
Douglas N. Greve, Ph.D.
MGH-NMR Center
greve@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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--
-Ryan