Dr. Inglesias
I am a developmental
psychologist studying memory and brain development in early childhood at
the University of Maryland. My lab has acquired whole-brain standard
resolution T1-weighted scans and ultra-high resolution T2-weighted scans
from 125 child participants aged 4-8 years. We are using your
automatic segmentation for hippocampal subregions to obtain volumes for
assessment in our study.
As we write up the results for
publication, I began to wonder if reviewers will ask for verification
that the automatic segmentation is valid for our young age group. I know
you tested Alzheimer's and an elderly sample in your paper, so I suspect
it is valid for a variety of populations. But I am writing to inquire
your thoughts on this issue. Do you think verification is needed? If
so, would you suggest we hand trace a subset of our data to verify the
automatic methods? I would appreciate any advise as to how to best
approach this.
Thank you, in advance, for your consideration of my inquiry.