Hi,

    To be specific, I'm trying to reconstruct arcuate fasciculus (refer to SLFT according to your paper 2011) in patients who suffered from frontal or temporal or parietal gliomas. I noticed that TRACULA was used to study neuropsychiatry and neurodegeneration diseases, such as schizophrenia, autism etc. When it comes to organic diseases, like brain tumor, white matter structures may be pushed or deformed due to mass effect. So my question is should I involve the patients in the training set? What can I do to succeed in reconstruction of arcuate fasciculus using TRACULA in my research? Thanks for your time.

BW,

yang

Hi - It's hard to predict in advance what will happen without trying it
out. A lot will depend on the size/position/nature of the tumor. Some
tumor patients will go through just fine, other will have issues. If the
freesurfer segmentation works, then tracula will work too.

Best,
a.y

On Thu, 2 Jun 2016, yangfuxing wrote:

> Dear professor,
>     I'm a postgraduate of neurosurgery. Recently, I'm interested in cortical
> parcellation and subcortical segmentation using freesurfer. In my study, all
> patients have brain tumors. So I begin to wonder if "recon-all" can still be
> applied to these subjects, or in other word, is it possible that
> freesurfer's automated brain segmentation could be applied to brain tumor
> patients because their normal structures were changed? If I just run it
> regularly according to fswiki, would the outcome be accurate?
>     Second question is about automatic tractography using TRACULA.
> Similarly, I'd like to use "trac-all" to reconstruct arcuate fasciculus in
> patients with brain tumor, is it possible? How can I set up the
> configuration? Hope to hear from you soon. Best wishes!
> Sincerely
>
>
_______________________________________________
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer


The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.