Dear All,
We are dealing with MPRAGE data acquired
at a 3.0T MRI scanner and analyzed with FS 3.0.5.
Images belong to a group of Multiple Sclerosis
patients.
We would like to ask some questions and we
apologize for the fact that we have quite a number of them J
First, regarding measurements coming from mris_anatomical_stats:
1) What is exactly included in total WM volume?
2) Is total WM volume the sum of left and right WM hemisphere
or just the WM volume from the side we specify (but if this is case, why we got
the same values after running mris_anatomical_stats for lh and rh hemisphere) ?
3) Since there are many WM lesions (with many juxta-cortical lesions that
need manual editing), we were wondering if total WM volume does include the
WM hypointensities as well or those are just treated separately.
4) Does the total GM volume include the volume of the
subcortical structures and cerebellum or just refer to the cortical GM volume?
Second, some other questions on the aseg.stat
file:
1) What is exactly included in CSF label? Does it comprehend the CSF
in the ventricles + the sulcal CSF, or just the the sulcal CSF?
2) Does the volume of the WM hypointensities manually edited (which
happens very often with MS lesions close to the cortex) end up in the WM
hypointensities volume?
Last, as we are interested in measuring subjects’
BPF, we were wondering which would be the best way to compute it?
Thanks a lot in advance,
Antonio
Antonio Gallo, MD
NIB-NINDS-NIH
Building 10, Room 5B16
ph #: 001-301-402.6391
fax #: 001-301-402.0373
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