Hi list,<br><div><br></div><div>I'm performing qdec. This my file.dat</div><div><br></div><div><div>1 &nbsp;diagnosis &nbsp;discrete 2</div><div>&nbsp; &nbsp; 1 &nbsp;Pathology</div><div>&nbsp; &nbsp; 2 &nbsp;Controls</div><div>2 &nbsp;Thickness_lh &nbsp;continuous 0</div><div>3 &nbsp;Thickness_rh &nbsp;continuous 0</div><div>4 &nbsp;NPStest &nbsp;continuous 0</div><div>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Continuous Factors: &nbsp; &nbsp; &nbsp; &nbsp; Mean: &nbsp; &nbsp; &nbsp; StdDev:</div><div>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; ------------------- &nbsp; &nbsp; &nbsp; &nbsp; ----- &nbsp; &nbsp; &nbsp; -------</div><div>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;Thickness_lh &nbsp; &nbsp; &nbsp; &nbsp; 2.643 &nbsp; &nbsp; &nbsp; &nbsp; 0.116</div><div>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;Thickness_rh &nbsp; &nbsp; &nbsp; &nbsp; 2.630 &nbsp; &nbsp; &nbsp; &nbsp; 0.099</div><div>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; NPStest &nbsp; &nbsp; &nbsp; &nbsp; 0.774 &nbsp; &nbsp; &nbsp; &nbsp; 1.203</div><div><br></div><div>Number of subjects: &nbsp; 31</div><div>Number of factors: &nbsp; &nbsp;4 (1 discrete, 3 continuous)</div><div>Number of classes: &nbsp; &nbsp;2</div><div>Number of regressors: 8</div></div><div><br></div><div><br></div><div>NPStest is scored from 0 to 8.</div><div><br></div><div><br></div><div>Qdec produces this error:&nbsp;</div><div><br></div><div><br></div><div><div>Creating output directory /Applications/freesurfer/subjects/subject_prova/qdec/Untitled</div><div>Loading y from /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/y.mgh</div><div>INFO: gd2mtx_method is dods</div><div>Saving design matrix to /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/Xg.dat</div><div>Normalized matrix condition is 1e+08</div><div>Design matrix ------------------</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.495 &nbsp; 0.000;</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.712 &nbsp; 0.000;</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.671 &nbsp; 0.000;</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.728 &nbsp; 0.000;</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.646 &nbsp; 0.000;</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.555 &nbsp; 0.000;</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.750 &nbsp; 0.000;</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.555 &nbsp; 0.000;</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.784 &nbsp; 0.000;</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.586 &nbsp; 0.000;</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.641 &nbsp; 0.000;</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.561 &nbsp; 0.000;</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.545 &nbsp; 0.000;</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.495 &nbsp; 0.000;</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.769 &nbsp; 0.000;</div><div>&nbsp;1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.740 &nbsp; 0.000;</div><div>&nbsp;0.000 &nbsp; 1.000 &nbsp; 0.000 &nbsp; 2.000 &nbsp; 0.000 &nbsp; 2.526;</div><div>&nbsp;0.000 &nbsp; 1.000 &nbsp; 0.000 &nbsp; 2.000 &nbsp; 0.000 &nbsp; 2.761;</div><div>&nbsp;0.000 &nbsp; 1.000 &nbsp; 0.000 &nbsp; 2.000 &nbsp; 0.000 &nbsp; 2.521;</div><div>&nbsp;0.000 &nbsp; 1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.592;</div><div>&nbsp;0.000 &nbsp; 1.000 &nbsp; 0.000 &nbsp; 2.000 &nbsp; 0.000 &nbsp; 2.555;</div><div>&nbsp;0.000 &nbsp; 1.000 &nbsp; 0.000 &nbsp; 2.000 &nbsp; 0.000 &nbsp; 2.671;</div><div>&nbsp;0.000 &nbsp; 1.000 &nbsp; 0.000 &nbsp; 3.000 &nbsp; 0.000 &nbsp; 2.559;</div><div>&nbsp;0.000 &nbsp; 1.000 &nbsp; 0.000 &nbsp; 3.000 &nbsp; 0.000 &nbsp; 2.469;</div><div>&nbsp;0.000 &nbsp; 1.000 &nbsp; 0.000 &nbsp; 4.000 &nbsp; 0.000 &nbsp; 2.691;</div><div>&nbsp;0.000 &nbsp; 1.000 &nbsp; 0.000 &nbsp; 2.000 &nbsp; 0.000 &nbsp; 2.522;</div><div>&nbsp;0.000 &nbsp; 1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.553;</div><div>&nbsp;0.000 &nbsp; 1.000 &nbsp; 0.000 &nbsp; 2.000 &nbsp; 0.000 &nbsp; 2.702;</div><div>&nbsp;0.000 &nbsp; 1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.738;</div><div>&nbsp;0.000 &nbsp; 1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.789;</div><div>&nbsp;0.000 &nbsp; 1.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 0.000 &nbsp; 2.651;</div><div>--------------------------------</div><div>ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08</div><div>--------------------------------</div><div>Possible problem with experimental design:</div><div>Check for duplicate entries and/or lack of range of</div><div>continuous variables within a class.</div><div>If you seek help with this problem, make sure to send:</div><div>&nbsp; 1. Your command line:</div><div>&nbsp; &nbsp; mri_glmfit --y /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/y.mgh --fsgd /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/qdec.fsgd dods --glmdir /Applications/freesurfer/subjects/subject_prova/qdec/Untitled --surf fsaverage lh --label /Applications/freesurfer/subjects/subject_prova/fsaverage/label/lh.aparc.label --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Avg-Intercept-thickness.mat --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Avg-thickness-NPStest-Cor.mat --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Diff-Controls-Pathology-Intercept-thickness.mat --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Diff-Controls-Pathology-Cor-thickness-NPStest.mat&nbsp;</div><div>&nbsp; 2. The FSGD file (if using one)</div><div>&nbsp; 3. And the design matrix above</div><div>Error in Analyze: command failed: mri_glmfit --y /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/y.mgh --fsgd /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/qdec.fsgd dods --glmdir /Applications/freesurfer/subjects/subject_prova/qdec/Untitled --surf fsaverage lh --label /Applications/freesurfer/subjects/subject_prova/fsaverage/label/lh.aparc.label --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Avg-Intercept-thickness.mat --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Avg-thickness-NPStest-Cor.mat --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Diff-Controls-Pathology-Intercept-thickness.mat --C /Applications/freesurfer/subjects/subject_prova/qdec/Untitled/contrasts/lh-Diff-Controls-Pathology-Cor-thickness-NPStest.mat</div></div><div><br></div><div>I don't understand what's happen?</div><div><br></div><div>Thanks,</div><div><br></div><div><br></div><div>Stefano</div><br>
<br>