On 5/5/17 5:06 AM, John Anderson wrote:

Dear Doug,

I have Bold fMRI data (6 minutes of acquisition which is equal to 180 volume for every run). The total number for images is 140 (50 controls and 90 patients). I plan to use FSFAST (FS V6.0) to study:

1. The difference between the groups in global functional connectivity

2. Seed-based functional connectivity analysis depending on an ROI for a difference in a voxel-wise analysis between PET images for the same subjects.

My questions are:

1. In this data set I have only one run for every subject. I am wondering if FSFAST can analyze fMRI data (one run per subject).

Yes, no problem

2. FSFAST depends on the recons, meaning it depends on the ROIs in wmparc, aseg and apare+aseg atlases. Can FSFAST accept an external ROI for seed based functional connectivity analysis?

Yes, just create an ROI as a mask in the conformed anatomical space and put the volume in the subject/mri folder. Then when you run fcseed-sess, spec that volume with -seg and specify the ROI code with -segid. Eg, if your volume was myroi.mgz and the value that the roi takes in that volume was 3, then -seg myroi.mgz -segid 3

I highly appreciate your advice

John

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