Dear Freesurfer experts,

 

A while ago I sent the question below to the FS mailinglist, but it was never answered… Would anyone be able to help me with this issue?

 

Thank you very much in advance!

 

Best wishes,

Lizanne

 

 

 

Dear Freesurfer experts,

 

I am modelling multiple covariates (age, SES, nr of symptoms and nr of

symptoms2) in one subject group. For the quadratic term I added a column in

the fsgd-file. I want to visualize the effect of nr of symptoms, either

their linear or their quadratic effects. I therefore made two contrasts:

 

The effect of symptoms:

 

0 0 1 0

 

And the effect of symptoms2:

 

0 0 0 1

 

 

I would like to model these two effects together in one contrast, to visualize the total effect of symptoms. I tried the following contrast:

 

 

0 0 1 0

 

0 0 0 1

 

 

But the result is very different from the two individual contrasts. I get

large (non-overlapping) clusters of significant effect in the two separate

contrasts, but with the combined contrasts I get none.

What would be the appropriate contrast if I want

to visualize all regions with the effects of symptoms, including both linear AND quadratic effects?

 

Thank you very much for your help

 

Best wishes, Lizanne

 

 

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