I want to use Freesurfer-Samseg for MS lesion segmentation(cross-sectional). I have read the paper, accordingly I want to try the t1-flair combination in terms of the accuracy.

Do you have any experience with T1 images with contrast agent? I couldn't find anything related to those in the paper. Can I use t1 with contrast in a few patients if the patient doesn't have t1 image without contrast agent? i will declare this situation in the results.

Best,

Dilek