why would you do that? And how are you projecting? The best way to do it is to sample it onto the individual subject surface, then use mri_surf2surf to map from one to another?

On Mon, 29 Mar 2010, Vadim Axel wrote:

Thank you a lot, Bruce.
One quick follow-up question: is it really bad is to project the activations
on not_the_same_subject_anatomy? For example (attached), I have ran
recon-all for two normalized SPGRs ('ka' and 'nz'). The general shape of
brains is similar, though the sulci / gyri are in different places / form.
Now I project the activations of one of them ('ka') to anatomies of itself
and of 'nz'. The difference is dramatic. Does my demo make sense?

On Mon, Mar 29, 2010 at 2:42 PM, Bruce Fischl <fischl@nmr.mgh.harvard.edu>wrote:

Hi Vadim

the only problem will be that you've introduced an extra interpolation and
the associated smoothing into your data. I suspect it will reduce the
accuracy of the models for things like thickness estimation, but otherwise
should be fine for e.g. functional overlaying.

cheers
Bruce



On Mon, 29 Mar 2010, Vadim Axel wrote:

 Dear experts,

I run my statistical analysis in SPM, while after coregistration I
normalize
my data (SPGR and EPI). Since my models and activations images are based
on
normalized data it's natural for me to use the normalized SPGR as an input
for freesurfer  inflation. Is it a good enough? Since I run inflation for
each individual brain, I basically can do it for non-normalized anatomy,
which is preferable, I think. However, then the coordinates are not MNI /
Talariach. Attached the comparison of activations for normalized (left
side)
vs. non-normalized. It looks pretty similar, though the brains look of
different shape. So, am I OK to do it on normalized brain?

Thanks for help,
Vadim

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