Hi Priti - Thanks for your help. The inter-subject registration seems to have run OK, but there must be something wrong with the intra-subject registration. When I try to view it using freeview, it's completely dark - I don't see a brain at all. Is there a way to troubleshoot this?

Thanks,

Kiely 

On Wed, May 9, 2012 at 2:08 PM, Priti Srinivasan <rspriti@nmr.mgh.harvard.edu> wrote:
Hi Kiely,

Have you checked your inter and intra subject registrations? The control
points going off the dwi is not only for one paths but for all the paths.
If the registration goes terribly wrong, this can happen. You can take a
look at

/dmri/lowb_brain_anat.flt.nii.gz (For intra subject registration diff-anat)

and

/dmri/brain_anat_mni.nii.gz (For inter-subject registration anat-mni)

I would start by checking that first.

Priti

> Hello--
>
> I have run Tracula successfully for ~75 healthy subjects. However, the
> pathway reconstruction seems to fail for a handful of people. I've
> attached
> the log file for one of these subjects. It appears that the control points
> are not within the dwi. A similar problem occurred in a subject with
> substantial signal loss in the dwi, but that doesn't seem to be the case
> for this particular person. I have been creating the entire set of tracts,
> but at this point, I'm only interested in the SLFt and SLFp.
>
> Thanks,
>
> Kiely
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--
Kiely M. Donnelly, M.A.
Doctoral Candidate, Clinical Neuropsychology
University of Cincinnati