Dear Prof. Fischl

Thanks for the prompt response.

The more specific reason of my query is that there was a difference in statistical significance between two FS versions.

For example, the result of group comparison of left thalamic volumes (ANCOVA controlling for age and eICV) is statistically significant (p = 0.04) when using FS 5.1, whereas the result is no longer significant at all (p = 0.28) in case of FS 5.3.

I'm a little confused about this discrepancy.

Which result should I trust?

Thank you in advance for your comments.

Kim

2014-03-23 2:59 GMT+09:00 Bruce Fischl <fischl@nmr.mgh.harvard.edu>:

Hi Kim

there are probably lots of little reasons for the differences. This is
always true for different versions, and the reason we never mix versions

cheers
Bruce
On

Sun, 23 Mar 2014, jh kim wrote:

> Dear FS lists
> When I measured subcortical GM volumes in the same subjects by using both
> version 5.1 and 5.3, I have observed a considerable difference in volumes
> between the two versions.
> For instance, please see the left thalamic volumes below.
> I cannot figure out why there is much difference between the versions.
> Which result is more reliable?
>
> Left-Thalamus-Proper_5.3
> Left-Thalamus-Proper_5.1
> 10313
> 9757
> 8924.8
> 7746
> 9834.8
> 8287
> 7935.2
> 7034
> 8764.1
> 7747
> 9411.8
> 8037
> 7636.7
> 8051
> 9334.7
> 8255
> 10024.3
> 8171
> 8757.7
> 6900
> 9540.9
> 8316
> 9294.4
> 8369
> 8091
> 7366
> 9103.7
> 7818
> 9310.2
> 7974
> 7583
> 6872
> 9838.9
> 8911
> 8829.6
> 8004
> 9094.8
> 6973
> 9492.3
> 8922
> 8821.6
> 7691
> 7971.6
> 7376
> 9901.2
> 8936
> 9773.9
> 8855
> 9283.7
> 7615
> 8801.6
> 7690
> 8505.1
> 7325
> 8981
> 7258
> 9644.7
> 8860
> 9104.2
> 8298
> 8494.8
> 7402
> 9024.9
> 7721
> 8117.8
> 7226
> 8001.8
> 7548
> 8392.3
> 7668
> 8606.6
> 8173
> 9126.7
> 7595
> 8093
> 7885
> 8317.7
> 7157
> 10556
> 9307
> 8669.6
> 8374
> 8034.7
> 7338
> 8148.5
> 7276
> 9048.1
> 8064
> 8160.1
> 7014
> 8747.9
> 7894
> 8329.9
> 6866
> 8415.8
> 8189
> 9246.9
> 8256
> 8194.1
> 7183
> 9629.2
> 9579
> 7688.2
> 6398
> 8349.2
> 8238
> 8366.2
> 7348
> 8436.5
> 7616
> 8372.3
> 6977
> 9396.4
> 7589
> 9327.5
> 7684
> 10001.8
> 8627
> 9762.4
> 9228
> 8841
> 8532
> 8342.4
> 8024
> 8645.7
> 7725
>
> Any comment would be appreciated.
> Thank you.
>
> Kim
>
>

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