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# cvs_version 7.2.0
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On 8/30/2022 12:51 PM, Dilek Özkan wrote:
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Hello dear all,
I use Freesurfer-Samseg for MS lesion segmentation(cross-sectional).
I use the T1 and Flair for this. (just these are inputs) I registered flair and t1 to DIR for every patient.(My manual lesion masks are on DIR imaging.) I controlled the registrations
At the beginning i didnt change initial threshold of run_samseg. (default value)
I created a binary lesion mask using different threshold.
threshold 0.1= dice 0,604
threshold 0.05= dice 0.611threshold 0.001 = dice 0.599
Do you have any recommendations to increase the dice? It seems that with this way It can't go up about 0.6
Best,Dilek
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