Dear Freesurfer-list,<br><br>Please excuse me if this question sounds very simple. I work with lesion brains and I want to overlay the group level result (sig.mgh) onto individual brains to check whether it covers the lesion (which we don&#39;t want). I first used mri_surf2vol to convert sig.mgh to a volume. I then mri_vol2vol to normalize the individual T1.mgz to the fsaverage T1, but when I overlaid the sig.mgz onto the normalized T1, it didn&#39;t look well-registered (see attached jpeg). However, when I overlaid the same sig.mgh onto the fsaverage T1, it looked completely fine. I&#39;m wondering if anyone could tell me how to better register the individual T1 so I can check whether the individual lesion overlaps with the group level results? Some of the brains went through tkregister2 and the segmentation looked fine afterwards. <br>
<br>Any guidance would be much appreciated! <br><br>Regards, <br>Catherine<br>