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Hello freesurfers,

I have some questions about the output variables of Freesurfer:

1. In the case of brain volume normalization, do I need to normalize all the volumetric results to the eTIV or just the subcortical volumes?

2. Are there any formulas other than simple division in order to normalize the volumes?

3. How are the .ThckStd values (like FS_R_Insula_ThckStd) calculated? What does the "std" mean here?

4. I believe that the surface area outputs are also affected by brain size differences in the population. Are there any reference values in the Freesurfer outputs to which surface areas can be normalized?

Thank you in advance for your help.

Best regards,
Yunus


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Yunus Soleymani

Ph.D. Candidate of Neuroimaging
Tehran University of Medical Sciences

+98 914 526 9298
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