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Hi Douglas,

Thanks for your reply. We used different tracers for diagnosis of AD or other neurodegenerative diseases, including PIB, FDG, Flutemetamol and TAU. If an SUV analysis is used, is it done by mri_gtmpvc? Is there any subsequent analysis needed?

This is my mri_gtmpvc command:

mri_gtmpvc \

  --i $SUBJECTS_DIR/sub-QM001/pet/sub-QM001_ses-001_trc-C11PIB_rec-05MINS_run-001_pet.nii.gz \

  --reg $SUBJECTS_DIR/sub-QM001/pet/sub-QM001_ses-001_trc-C11PIB_rec-05MINS_run-001_pet.reg.lta \

  --psf 6 \

  --seg $SUBJECTS_DIR/sub-QM001/mri/gtmseg.mgz \

  --default-seg-merge  \

  --auto-mask 1 .01 \

  --mgx .01 \

  --o $SUBJECTS_DIR/sub-QM001/pet/gtmpvc.output

Is this command okay?

Thanks,

Angel

---

From: freesurfer-bounces@nmr.mgh.harvard.edu <freesurfer-bounces@nmr.mgh.harvard.edu> on behalf of Douglas N. Greve <dgreve@mgh.harvard.edu>
Sent: Wednesday, March 20, 2024 11:27 PM
To: freesurfer@nmr.mgh.harvard.edu <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] PetSurfer: Can kinetic modeling be applied to PET data with single frame?

 

you cannot apply kinetic modeling to one frame. What is you ligand? For a one frame acquisition, you usually use an SUV analysis.

On 3/20/2024 12:03 AM, WONG Wan Wa wrote:

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Hi experts,

As stated in the subject, can kinetic modeling be applied to PET data with only one frame? Or we just stop at ROI analysis without kinetic modeling?

Best,

Angel

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