On Mon, Apr 10, 2017 at 2:21 PM, Douglas N Greve <greve@nmr.mgh.harvard.edu> wrote:

sorry, I would use these two

TVV = left lateral ventricle + left inf lateral ventricle + right
lateral ventricle + right inf lateral ventricle + 3rd ventricle
+ 4th ventricle + 5th ventricle + choroid plexus

TBV = BrainSegVolNotVent

On 04/10/2017 09:43 AM, Gullickson, James wrote:
> Hi Doug,
>
> To clarify: to calculate VBR, I need two things: a measure of TBV
> /and/ and measure of TVV. I'm just wondering what the best way to
> derive each of these is.
>
> Thanks,
>
> James
>
> On Fri, Apr 7, 2017 at 11:24 AM, Douglas N Greve
> <greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>> wrote:
>
> I would use the TVV
>
>
> On 04/06/2017 06:28 PM, Gullickson, James wrote:
> > Doug,
> >
> > Thanks for your reply.
> >
> > Difference between the two TVV methods ranges between 1-6%
> > Difference between the two TBV methods ranges between 2-4%
> >
> > Basically, my question is two-fold:
> >
> > a) what is the most accurate representation of total ventricular
> volume
> > b) what is the most accurate representation of total brain
> volume (all
> > parenchyma)
> >
> > Best,
> >
> > James
> >
> > On Thu, Apr 6, 2017 at 3:17 PM, Douglas N Greve
> > <greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>
> <mailto:greve@nmr.mgh.harvard.edu

> <mailto:greve@nmr.mgh.harvard.edu>>> wrote:
> >
> > that looks right. how different are the values?
> >
> >
> > On 04/05/2017 10:58 AM, Gullickson, James wrote:
> > > Hello all,
> > >
> > > I want to calculate a Ventricle-to-Brain ratio (VBR) as a
> measure of
> > > parenchymal atrophy using Freesurfer version 5.3.0. I have
> tried
> > to go
> > > about this using the aseg.stats output (using
> asegstats2table),
> > but am
> > > running into inconsistencies.
> > >
> > > The basic calculation for VBR is:
> > >
> > > (Total Ventricular Volume/Total Brain Volume) * 100
> > >
> > > i.e. Bigler, E. D. (2013). Traumatic brain injury,
> neuroimaging, and
> > > neurodegeneration. /Frontiers in human neuroscience/, /7/,
> 395.
> > >
> > >
> > > What is the best way to get Total Ventricular Volume (TVV)
> and Total
> > > Brain Volume (TBV) for this calculation? I have tried
> several ways,
> > > which lead to different values:
> > >
> > > TVV = left lateral ventricle + left inf lateral ventricle
> + right
> > > lateral ventricle + right inf lateral ventricle + 3rd
> ventricle
> > + 4th
> > > ventricle + 5th ventricle + choroid plexus
> > >
> > > which gives me a different result than
> > >
> > > TVV = BrainSegVol - BrainSegVolNotVent
> > >
> > >
> > > and for TBV
> > >
> > > TBV = TotalGrayVol + CorticalWhiteMatterVol
> > >
> > > which differs from
> > >
> > > TBV = BrainSegVolNotVent
> > >
> > >
> > > Thank you for your help,
> > >
> > > James Gullickson
> > >
> > >
> > >
> > >
> > >
> > > _______________________________________________
> > > Freesurfer mailing list
> > > Freesurfer@nmr.mgh.harvard.edu
> <mailto:Freesurfer@nmr.mgh.harvard.edu>

> > <mailto:Freesurfer@nmr.mgh.harvard.edu
> <mailto:Freesurfer@nmr.mgh.harvard.edu>>
> > >
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
> <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer>
> > <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
> <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer>>
> >
> > --
> > Douglas N. Greve, Ph.D.
> > MGH-NMR Center
> > greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>
> <mailto:greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>>
> > Phone Number: 617-724-2358 <tel:617-724-2358>
> <tel:617-724-2358 <tel:617-724-2358>>
> > Fax: 617-726-7422 <tel:617-726-7422> <tel:617-726-7422
> <tel:617-726-7422>>
> >
> > Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
> <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>
> > <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
> <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>>
> > FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
> <https://gate.nmr.mgh.harvard.edu/filedrop2>
> > <https://gate.nmr.mgh.harvard.edu/filedrop2
> <https://gate.nmr.mgh.harvard.edu/filedrop2>>
> > www.nmr.mgh.harvard.edu/facility/filedrop/index.html
> <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html>
> > <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html
> <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html>>
> > Outgoing:
> > ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
> <ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/>
> > <ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
> <ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/>>
> >
> > _______________________________________________
> > Freesurfer mailing list
> > Freesurfer@nmr.mgh.harvard.edu
> <mailto:Freesurfer@nmr.mgh.harvard.edu>
> <mailto:Freesurfer@nmr.mgh.harvard.edu
> <mailto:Freesurfer@nmr.mgh.harvard.edu>>
> > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
> <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer>
> >

> <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
> <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer>>
> >
> >
> > The information in this e-mail is intended only for the
> person to
> > whom it is
> > addressed. If you believe this e-mail was sent to you in
> error and
> > the e-mail
> > contains patient information, please contact the Partners
> > Compliance HelpLine at
> > http://www.partners.org/complianceline
> <http://www.partners.org/complianceline>
> > <http://www.partners.org/complianceline
> <http://www.partners.org/complianceline>> . If the e-mail was sent
> > to you in error
> > but does not contain patient information, please contact the
> > sender and properly
> > dispose of the e-mail.
> >
> >
> >
> >
> > _______________________________________________
> > Freesurfer mailing list
> > Freesurfer@nmr.mgh.harvard.edu
> <mailto:Freesurfer@nmr.mgh.harvard.edu>
> > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
> <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer>
>
> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>
> Phone Number: 617-724-2358 <tel:617-724-2358>
> Fax: 617-726-7422 <tel:617-726-7422>
>
> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
> <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>
> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
> <https://gate.nmr.mgh.harvard.edu/filedrop2>
> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
> <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html>
> Outgoing:
> ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
> <ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/>
>
> _______________________________________________
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu <mailto:Freesurfer@nmr.mgh.harvard.edu>
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
> <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer>
>
>
>
>
> _______________________________________________
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

--
Douglas N. Greve, Ph.D.
MGH-NMR Center
greve@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/

_______________________________________________
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer