So then how does one determine what should go into the Threshold min box? (If it's usually p<0.05 should the clusterwise corrected Threshold min be 1.3?)

Natasha 


On Tue, Jan 28, 2014 at 12:30 PM, Douglas N Greve <greve@nmr.mgh.harvard.edu> wrote:

On 01/28/2014 03:26 PM, Natasha Haris wrote:
Oops sorry!

I guess my question then is, after running the monte carlo simulation with this cluster-forming threshold (p<0.01), is there a specific corrected (clusterwise) threshold I can/am supposed to place in the Threshold min box? Or are these two not related in any way.
They are not related. The clusterwise threshold is what you would use when you go to convince a reviewer that the effect is significant. Usually, this is .05.

Natasha



On Tue, Jan 28, 2014 at 12:11 PM, Douglas N Greve <greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>> wrote:


    Hi Natasha, please remember to post to the list! When you say a
    different set of blobs, do you mean that none of the original
    blobs are there? Or do some of the blobs just disappear? Note that
    the threshold you use in the simulation is not related to the
    "Threshold Min". In this case, the Threshold Min is the corrected
    threshold (clusterwise). The threshold used in the simulation is
    the "cluster forming threshold"

    doug






    On 01/28/2014 02:51 PM, Natasha Haris wrote:

        Thank you! Additionally, after running the clusterwise Monte
        carlo simulation with p<0.01 I get a blob. After placing this
        value in the threshold min box I get a different set of blobs
        on my image. Why is this?

        Natasha


        On Tue, Jan 28, 2014 at 11:41 AM, Douglas N Greve
        <greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>
        <mailto:greve@nmr.mgh.harvard.edu
        <mailto:greve@nmr.mgh.harvard.edu>>> wrote:


            Yes, when looking at the corrected images, the Threshold Min
            because the clusterwise threshold. So if you want to see only
            clusters that have a clusterwise p<.05, set that threshold
        to 1.3

            doug






            On 01/28/2014 02:24 PM, Natasha Haris wrote:

                The clusterwise simulation runs with a p<0.05
        threshold value
                and a blob appears. However, am I supposed to enter this
                threshold value corresponding to p<0.05 (namely 1.3)
        into the
                box labeled threshold min= ?


                On Mon, Jan 27, 2014 at 8:43 AM, Douglas N Greve
                <greve@nmr.mgh.harvard.edu
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        <mailto:greve@nmr.mgh.harvard.edu>>
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        <mailto:greve@nmr.mgh.harvard.edu>

                <mailto:greve@nmr.mgh.harvard.edu
        <mailto:greve@nmr.mgh.harvard.edu>>>> wrote:


                    On 01/24/2014 11:54 AM, Natasha Haris wrote:
                    > Dear Freesurfers,
                    >
                    > I am slightly confused about the monte carlo
        simulation.
                    >
                    > First off, I only find a blob when I run the p<0.05
                threshold
                    level and don't see anything else when I run
        simulations
                with p
                    less than that. What does this mean?
                    Which threshold level? clusterforming/voxelwise or
                clusterwise? If
                    clusterwise, then it just means that you have a
        cluster
                whose p
                    value is
                    just under .05 so you lose it by going to a more
        stringent
                threshold.
                    >
                    > Additionally, when I click on any question of
        interest after
                    running this p<0.05 simulation (for ex. "Does the
        average
                    thickness, accounting for Group, differ between
        male and
                female?"
                    I get the same blobs that I found before I ran this
                precomputed
                    simulation. Is the simulation not running
        correctly? Am I
                supposed
                    to enter this threshold value (1.3) into the area
        marked
                Threshold
                    min= and max=5.
                    Are you sure it is exactly the same? Look to see
        if there
                are some
                    very
                    small blobs that disappear. Otherwise, it may be
        that the
                blobs
                    you have
                    are all significant.
                    >
                    > Thank you for your help!
                    > Natasha
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