Hi Lanbo,

you could look at longitudinal changes of the left-right difference in volume per ROI. Or do you mean on the cortical thickness map (I have never done that, but probably works similarly, construct left -right registration, compute difference, then run the LME on that).

Best, Martin


Am 17.12.2017 um 17:54 schrieb lanbo Wang:
Hi, all experts.
I want to compare changes rate between left and right hemisphere of longitudinal data, How should I do that, how to combine xhemi with two stage or LME?

Best,
Lanbo


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