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Hi Doug, thank you for the response. I would appreciate if you advice any better method to compute the SNR for PET signal within an ROI (e..g. thalamus)?

I used spmregister to move my PET images to Freesurfer space then I am thinking of using mri_segstat to generate SNR for the PET signal within an ROI, would you please suggest an efficient way to do it?

Thank you!

Yes, but know that the "SNR" as computed there is the spatial mean divided by the spatial standard dev. This is likely not the SNR that you want

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On August 14, 2018 5:07 PM, James Brown <John.anderso@protonmail.com> wrote:

Hi Freesurfer team,
I would like to use "mri_segstat" to compute SNR for regions of interest. My question is, if I use PET images as input does this mean that SNR will be computed for the PET signal in the ROIs?

Thanks for any help
John