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​Tricia Stefancin

Lab manager
Z-lab
Department of Psychology
The Ohio State University
From: Resnick, Patricia
Sent: Friday, April 21, 2023 12:29 PM
To: freesurfer@nmr.mgh.harvard.edu
Subject: repeated measures anova for 4 treatments by 2 timepoints
 
Hello,
I have a total of 8 subjects with 4 treatments (A/stim, A/sham, B/stim, B/sham) each with 2 timepoints (pre, post). I subtracted the pre-post images and I am trying to compare the differences between A/stim and A/sham, B/stim and B/sham, and A/stim and B/sham. I have run the mri_glmfit command below and get the following error: 

matrix is ill-conditioned or badly scaled, condno = 1.33391e+07


mri_glmfit --glmdir /fs/project/PAS1305/IMPACT/glm_analysis/motor/Motor-Fix/lh/ --y /fs/project/PAS1305/IMPACT/glm_analysis/motor/Motor-Fix/lh/sigLH.nii.gz --fsgd /fs/project/PAS1305/IMPACT/glm_analysis/motor/repeated_measures.fsgd doss --C /fs/project/PAS1305/IMPACT/glm_analysis/motor/TMS_stim-sham_repeated.mtx --C /fs/project/PAS1305/IMPACT/glm_analysis/motor/PBM_stim-sham_repeated.mtx --C /fs/project/PAS1305/IMPACT/glm_analysis/motor/PBM-TMS_stim_repeated.mtx --surf fsaverage lh --fwhm 0 --sim mc-full 500 2 corrp --sim-sign abs


Would someone be able to tell me why this is not going through?
Best,

​Tricia Stefancin

Lab manager
Z-lab
Department of Psychology
The Ohio State University