Hello Lee - thanks so much for your response. I looked into the document you referred me to and found a section on GE protocols here (page 3):

http://martinos.org/~andre/FreeSurfer_recommended_morphometry_protocols.pdf

I would appreciate your input on a few details.

First, the document indicates "min (9150ms) for the TR value. However, the minimum TR is about 8 ms when I prescribe a similar IR-FSPGR sequence. I may be missing something obvious, but:

a) Would that be 9.15 ms instead? (actually, the TR is not selectable when prescribing this 3D sequence).

Also, we are mostly interested in getting good whole-brain segmentation and, from what I gather, the document mentions that multiecho FLASH is the way to go for this.

b) Would the GE IR-FSPGR sequence specified in the protocol document still be OK for getting reliable whole-brain segmentation?

c) I take it then that there is no "GE-version" for the multiecho FLASH, correct?

Thanks again,

Antonio