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Hello Yiota,


the whole hippocampus value is a sum of all subregions except for the hippocampal fissure - best try to reproduce this in an example.


The recon-all pipeline also delivers a total hippocampal volume, but it is an entity/result of its own and produced independently of

the subfield segmentation. It indirectly also contains areas that in the subfield segmentation would go to the fissure.


There is several papers out that compared the two, generally the subfield based sum value is considered more reliable.


Best,

Philipp



Von: freesurfer-bounces@nmr.mgh.harvard.edu <freesurfer-bounces@nmr.mgh.harvard.edu> im Auftrag von Panayiota Ventura <panayiota.ventura@gmail.com>
Gesendet: Montag, 21. Juni 2021 21:27
An: freesurfer@nmr.mgh.harvard.edu
Betreff: [Freesurfer] Hippocampal Subfields/ASEG
 

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Hello,

I have a couple of questions concerning the hippocampal subfield extractions as well as the hippocampus extraction included in ASEG. I have looked around and tried to find as much information as possible about the two but I can't seem to find a clear answer. I'm hoping someone can help me out with this.

1. In the hippocampal subfields extraction, one of the labels is called "whole hippocampus". I would like to know what exactly is meant by that? In other words, what hippocampal regions are included in this "whole hippocampus" label?

2. The ASEG atlas also includes a hippocampus extraction. However this value is different from that of the hippocampal subfield extraction. What hippocampal regions are being included in this hippocampal extraction.

3. Which of the two would be a better estimate of hippocampal volume?

Thank you for your time and help!

Kind regards,

Yiota Ventura