Dear Freesurfer experts,

Regarding the recommended MRI protocol for FreeSurfer,

We have some questions.

I read that using T1 Multiecho MPRAGE and T2-SPACE FLAIR in the Freesurfer analysis would be helpful to enhance a Freesurfer result.

T2-SPACE FLAIR image must have both same voxel resolution (1x1x1) and bandwidth(651 Hz/px) equal to T1 image?

Is it possible to change voxel resolution of the T2-SPACE FLAIR to lower one (eg. 2x2x2), guaranteeing same Freesurfer result?

And one MRI expert recommended that T2-SPACE FLAIR should be acquired in axial orientation, not in sagittal orientation.

Is it right?

I'm wondering what the difference is between axial and sagittal acquisition orientation in the aspect of MRI quality and analysis result.

Best regards,

Jeongsik Kim