Hi,<br><br>We run the freesurfer stable v4.4.0 on our Linux computer (Ubuntu 9.04). The program finishes without any error. However, we find the stats files (in the /subject/stats) from repeated runs  on the same subject vary widely in final outcome.  <br>

Meanwhile, we notice the item of the stable v4.5.0 release notes, which&#39;s  about the flag of -norandomness. It&#39;s said that the binaries in the recon-all stream are subject to variability due to usage of a random number generator (mris_smooth, mris_sphere, mris_topology_fixer, mris_topo_fixer and mris_ca_label). Is this realtive with our problem? Have anyone met this problem? <br>

Do the data need to rerun using Stable v4.5.0? To take into account the number of the subjects, is there any other method to fix it? <br><br>For example:<br>tail -2 &#39;thickness.lh.MT.songjunyi.txt&#39;<br># ColHeaders StructName NumVert SurfArea GrayVol ThickAvg ThickStd MeanCurv GausCurv FoldInd CurvInd<br>

lh.MT.songjunyi.label                    2330   1564   4584  2.548 0.684     0.146     0.062       52     6.5<br> tail -2 thickness.lh.MT.songjunyi_re1.txt<br># ColHeaders StructName NumVert SurfArea GrayVol ThickAvg ThickStd MeanCurv GausCurv FoldInd CurvInd<br>

lh.MT.songjunyi_re1.label                  2409   1631   4786  2.539 0.698     0.146     0.075       78     7.7<br> tail -2 thickness.lh.MT.songjunyi_re2.txt<br># ColHeaders StructName NumVert SurfArea GrayVol ThickAvg ThickStd MeanCurv GausCurv FoldInd CurvInd<br>

lh.MT.songjunyi_re2.label                  2341   1576   4659  2.558 0.694     0.143     0.058       39     6.0<br><br>Any help would be appreciated. Thanks.<br><br><br>