Hi Bruce,
 
  My data is loss from 35 to 40. But the uniform of sex is not  well from 40 to 55 and from 56 to 71. I did the correlation analysis between age and volume. I don't know how I can explain this problem. 
  Thanks again.

Sincerely,
Zheng  






At 2017-11-20 09:35:45, "Bruce Fischl" <fischl@nmr.mgh.harvard.edu> wrote: >Hi Zheng > >how uniform is your distribution? I'm hardly an expert on this, but I >wouldn't expect very large effects until you get into the older end of >that range. Have you scatter plotted your data? >Bruce >On Mon, 20 Nov 2017, 郑凤莲 >wrote: > >> >> Hi Bruce, >> >>     Thank you for your help. >>     I have  54 subjects, aged from 21 to 71 and only one group. I want to compare the change of >> hippocampus volume with age. The results before and after doing the correction for eTIV are the >> same. Where is wrong? Or if there is no error, how can I explain it in discussion? >> >> Thanks, >> Zheng >> >> >> >> >> >> At 2017-11-20 04:55:49, "Bruce Fischl" <fischl@nmr.mgh.harvard.edu> wrote: >> >Hi Zheng >> > >> >yes, I see. Maybe the effect is smaller than you have the power to see, or >> >there is no effect? You would need to give us more details for us to help. >> >Are you correcting for eTIV? What measure are you comparing? >> > >> >cheers >> >Bruce >> > On Sun, 19 Nov 2017, 郑凤莲 wrote: >> > >> >> Hi Bruce, >> >> >> >>      I am sorry for this situation.  >> >>      In the first way, there was an statistical difference in left hippocampus, but no difference >> in >> >> right hippocampus. In the second way, there was both no statistical difference in left or >> >> right  hippocampus. I don't know what causes this result.  >> >>      Can you understand me this time? >> >> >> >> Thanks, >> >> Zheng >> >> >> >> >> >> >> >> >> >> At 2017-11-18 22:58:56, "Bruce Fischl" <fischl@nmr.mgh.harvard.edu> wrote: >> >> >Hi Zheng >> >> > >> >> >no difference between what and what? >> >> > >> >> >cheers >> >> >Bruce >> >> >On Fri, 17 Nov 2017, 郑凤莲 wrote: >> >> > >> >> >> Hi professor, >> >> >> >> >> >>     I am using Freesurfer for DTI data. When I run 'mri_segstats', I >> >> >> got the result that there w >> >> as >> >> >> an obvious difference in left hippocampus, but no difference in right hippocampus. Then, I run >> >> >> segmentation of hippocampus subfields. The result showed there is no difference in total left >> or >> >> >> right hippocampus, and only in two right hippocampus subfields has significant difference. Why >> is >> >> >> there inconsistent result in two means?  >> >> >>     Thank you very much. >> >> >> >> >> >> Sincerely, >> >> >> Zheng >> >> >> >> >> >> >> >> >> >> >> >>   >> >> >> >> >> >> >> >> >> >> >> >> >> >> >> >> >>   >> >> >> >> >> >> >> >> >> >>   >> >> >>