I am trying to generate significance maps for a paired-difference analysis of cortical thickness using multiple pairs of siblings, and was wondering if there is a way to incorporate the family ID as a random effect/covariate in Freesurfer. Is it possible for
the family ID for each sibling pair to be used as a categorical/discrete variable to then see the effect of family on cortical thickness in addition to the main effects we are looking at? Any guidance would be greatly appreciated!
Best,
Casey
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Casey
Hopkinson
Clinical Research Coordinator Brain Genomics Laboratory Division of Psychiatric Neuroimaging Massachusetts General Hospital 149 13th Street, Charlestown,
MA, 02129 (p) 617.643.3215