yes
On 12/17/2013 10:06 PM, Rujing Zha wrote:
> Dear Doug,
> Thanks for your precious help.
> Considering the 2nd example, I just want to know whether some brain
> surface thickness correlate the score without subjects coming from
> control or patient group. I think my aim is the same as want you told
> me "test whether the score is equal to 0 or not". Am I right?
> Thanks.
> All the best.
> 2013-12-18
> ------------------------------------------------------------------------
> /Rujing Zha/
> ------------------------------------------------------------------------
> *发件人:*Douglas N Greve <greve@nmr.mgh.harvard.edu>
> *发送时间:*2013-12-18 00:31
> *主题:*Re: [Freesurfer] design matrix and contrast in fsgdf
> *收件人:*"freesurfer"<freesurfer@nmr.mgh.harvard.edu>
> *抄送:*
> That looks correct. The contrasts for the 2nd example will test whether
> the score is equal to 0 or not (and not an interaction between diagnosis
> and score). It is not wrong, but I just wanted to make sure you know
> what you are testing.
> doug
> On 12/17/2013 01:50 AM, Rujing Zha wrote:
> > Dear all,
> > I want to design a group t-test analysis and correlation analysis for
> > pial thickness. I have read the PPT of freesurfer.groupanalysis, and I
> > wrote a specific design matrix and contrast for my data. However it is
> > the first time that I design matrix in fsgdf by freesurfer. I didnot
> > confirm whether I wrote is correct. I need someone to help me review it.
>
> > I have two groups, four groups were classified as sex.(Is this
> > necessary or correct?)
> > Here is my design matrix in fsgdf for 2 group t-test:
> > GroupDescriptorFile 1
> > Title lh_ttest
> > Class con_male
> > Class con_female
> > Class pat_male
> > Class pat_female
> > Variables Age edu
> > Input subjid1 con_male 19 10
> > Input subjid2 con_male 20 20
> > Input subjid3 con_male 20 20
> > Input subjid4 con_male 19 10
> > Input subjid5 con_female 20 20
> > Input subjid6 con_female 20 20
> > Input subjid7 con_female 19 10
> > Input subjid8 pat_male 20 20
> > Input subjid9 pat_male 20 20
> > Input subjid10 pat_male 19 10
> > Input subjid11 pat_female 20 20
> > Input subjid12 pat_female 20 20
> > DefaultVariable Age
> > In this section, I just want to compare the patient group(class 3 and
> > 4) and control group(class 1 and 2) in thickness controling the age
> > and education by ANCOVA. Does this fsgdf implement ANCOVA?
> > Here is my contrast for this:
> > 0.5 0.5 -0.5 -0.5 0 0 0 0 0 0 0 0
> > Here is my design matrix in fsgdf for partial regression:
> > GroupDescriptorFile 1
> > Title lh_regression
> > Class con_male
> > Class con_female
> > Class pat_male
> > Class pat_female
> > Variables Age edu score1 score2
> > Input subjid1 con_male 19 10 20 30
> > Input subjid2 con_male 20 20 20 30
> > Input subjid3 con_male 20 20 20 30
> > Input subjid4 con_male 19 10 20 30
> > Input subjid5 con_female 20 20 20 30
> > Input subjid6 con_female 20 20 20 30
> > Input subjid7 con_female 19 10 20 30
> > Input subjid8 pat_male 20 20 20 30
> > Input subjid9 pat_male 20 20 20 30
> > Input subjid10 pat_male 19 10 20 30
> > Input subjid11 pat_female 20 20 20 30
> > Input subjid12 pat_female 20 20 20 30
> > DefaultVariable score1
> > In this section, I want to implement partial regression analysis(i.e.
> > score1 and score2) by controling the age,edu and sex.
> > Here is my contrast for score1:
> > 0 0 0 0 0 0 0 0 0 0 0 0 0.25 0.25 0.25 0.25 0 0 0 0
> > Here is my contrast for score2:
> > 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.25 0.25 0.25 0.25
> > Any reply will be highly appreciated.
> > Thanks.
> > All the best.
> > 2013-12-17
> > ------------------------------------------------------------------------
>
> > /Rujing Zha/
> >
> >
> > _______________________________________________
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> > Freesurfer@nmr.mgh.harvard.edu
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> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> greve@nmr.mgh.harvard.edu
> Phone Number: 617-724-2358
> Fax: 617-726-7422
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Douglas N. Greve, Ph.D.
MGH-NMR Center
greve@nmr.mgh.harvard.edu
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