doug-

thanks for all the help on this. another quick question:

when choosing the simulation type does the ending have to match the sim sign? for instance i see examples with 

--sim mc-z 10000 3 mc-z.pos.3 --sim sign pos

or 

--sim mc-z 10000 3 mc-z.neg.3 --sim sign neg

I guess what i am asking is what does the first sign (in the mc-z.(SIGN).3 mean?

michael

On Wed, Jun 13, 2012 at 2:26 PM, Douglas N Greve <greve@nmr.mgh.harvard.edu> wrote:
If you run it with --help, you will see this. let me know if this is not
clear.

6. Select the threshold sign (--sim-sign). This is the sign of the
   threshold used to create the clusters for cluster-wise correction
   of multiple comparisons. Options are abs (unsigned), pos
   (positive), and neg (negative). If you have an a priori hypothesis
   (eg, group1 > group2), then choose positive. If you don not know
   the sign, then use abs. Choosing a sign will yield stronger results
   (ie, smaller p-values), but you will lose the other sign.

The FWHM is obtained from the data (glmdir/fwhm.dat)

doug



On 06/13/2012 02:04 PM, mdkruepke@uwalumni.com wrote:
> Freesurfers-
>
> When correcting for multiple comparisons using:
> mri_glmfit-sim \
>    --glmdir lh.gender_age.glmdir \
>    --sim mc-z 5 4 mc-z.negative \
>    --sim-sign neg --cwpvalthresh 0.4\
>    --overwrite
> What does the sign mean (ie - the neg, pos, abs). Also for the mc-z
> simulation type do we no longer need to include the smoothness of our
> data (FWMH)?
>
> Michael D. Kruepke
> PhD - University of Illinois at Urbana-Champaign
> BA - Psych - University of Wisconsin-Madison
> mdkruepke@gmail.com <mailto:mdkruepke@gmail.com>
> (262)-483-7449
>
>
>
> _______________________________________________
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer

--
Douglas N. Greve, Ph.D.
MGH-NMR Center
greve@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

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Michael D. Kruepke
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BA - Psych - University of Wisconsin-Madison
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