Dear FS experts,

I’m processing the task-related fMRI using FS-FAST. I check the quality assurance and modified some subjects’ registration file(named new one as “register_manual.lta”). Then I do the first level analysis and group analysis.

My first question is: 

should I apply the new registration file into the following first level analysis and group analysis?

I found a tutorial may be answer my question , but I’m not sure about it.

http://surfer.nmr.mgh.harvard.edu/fswiki/MultiModalTutorialV6.0/FMRIGroupAnalysis#GroupROIfMRIAnalysis

Assemble the data using new registration file by the command:

    mris_preproc --target fsaverage --hemi lh \

       --iv  fbirn-101/ces.nii fbirn-101/register.lta \

       --iv  fbirn-103/ces.nii fbirn-103/register.lta \

       --iv  fbirn-104/ces.nii fbirn-104/register.lta \

       --projfrac 0.5 \

      --out lh.ces.mgh

Then use “mri_surf2surf”, “mri_glmfit” to do the group analysis.

My second question is: does the following two procedures both feasible for fMRI group analysis ?

1. Isxconcat-sess —>  mri_glmfit  —> mri-glnfit-sim
2. mris_preproc —> mri_surf2surf —> mri_glmfit  —> mri-glmfit-sim

Thank you! 

Regards,

Star