Hi Doug,

Sorry for the lack of information. We aren’t getting any specific error message or failure, it’s more so that we’re unable to get a good registration of the native space T1 to fsaverage. We tried several registration tools/commands, but an example of one of the best is below:

mri_coreg –s fsaverage –mov /path_to_T1.nii.gz –reg T1_lin_fsaverage.lta –regdat T1_lin_fsaverage.dat

We then visualized with the suggested tkregisterfv command:

tkregisterfv –mov /path_to_T1.nii.gz –targ /path_to_fsaverage/mri/brainmask.mgz –reg T1_lin_fsaverage.dat

See the relatively poor registration in the screenshot attached here.

I tried to overlay this ROI using tkmedit with the registration from the step above as suggested by the “VolumeRoiCorticalThickness” page, and get the suboptimal overlay in the second attached image.

Any suggestions for improving this registration?

Thanks,

Dan