Thanks Bruce.

I went over some more images with our PI and he was mostly satisfied with the pial/white segmentations. The real problem here is that our results look correct, except for they seem to be translated vertically by a small amount, comparing with what we see on the MRIs. What can we check to make sure everything is lining up correctly?

- Eli

On Thu, 2018-01-11 at 08:08 -0500, freesurfer-request@nmr.mgh.harvard.edu wrote:
Message: 5
Date: Wed, 10 Jan 2018 20:26:11 +0000
From: "Rockers, Elijah D." <edrockers@houstonmethodist.org>
Subject: [Freesurfer] reconstruction for very significant atrophy
To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Message-ID: <1515615971.3868.3.camel@houstonmethodist.org>
Content-Type: text/plain; charset="utf-8"

Hello,

We have some images that reflect severe atrophy in some subjects, in which gray matter is virtually undetectable on the MRI in some regions. However, upon checking the segmentations visually, the white/pial surfaces are reflecting a significant cortical thickness in these areas.

Is there perhaps any recon-all setting that might extend the white matter area out a little more aggressively than it does with the default settings?

Thanks,

- Eli

Houston Methodist. Leading Medicine. Houston Methodist is ranked by U.S. News & World Report as the No. 1 hospital in Texas for patient care. Houston Methodist is nationally ranked in 8 specialties and is designated as a Magnet hospital for excellence in nursing.  Visit us at  houstonmethodist.org. Follow us at  https://urldefense.proofpoint.com/v2/url?u=http-3A__twitter.com_MethodistHosp&d=DwICAg&c=QmPtDiFixEjkMvDKaP3E2Vb9C2z4M0PdarxyAHQ2iDQ&r=xbyrBxm81l6mG_XEX66jgCNTXfK3eVo30T9sVQVTz1Q&m=CAYGC0ZOLxrUbIrT78SfflAkZfYgzH8oPSEwBFUSUJg&s=PGX_syFrdnwd33_SeD4mJhR7objuPhwbK4lqK8C1R-M&e= and https://urldefense.proofpoint.com/v2/url?u=http-3A__facebook.com_HoustonMethodist&d=DwICAg&c=QmPtDiFixEjkMvDKaP3E2Vb9C2z4M0PdarxyAHQ2iDQ&r=xbyrBxm81l6mG_XEX66jgCNTXfK3eVo30T9sVQVTz1Q&m=CAYGC0ZOLxrUbIrT78SfflAkZfYgzH8oPSEwBFUSUJg&s=04vdwvZSyWy5SG-GmsAzYUrtI0lyfQC__axac_6TQzM&e=.  ***CONFIDENTIALITY NOTICE*** This e-mail is the property of Houston Methodist and/or its relevant affiliates and may contain restricted and privileged material for the sole use of the intended recipient(s). Any review, use, distribution or disclosure by others is strictly prohibited. If you are not the intended recipient (or authorized to receive for the recipient), please contact the sender and delete all copies of the message. Thank you.
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------------------------------

Message: 6
Date: Wed, 10 Jan 2018 15:28:25 -0500 (EST)
From: Bruce Fischl <fischl@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] reconstruction for very significant atrophy
To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Message-ID:
        <alpine.LRH.2.20.1801101527330.32719@gate.nmr.mgh.harvard.edu>
Content-Type: text/plain; charset=US-ASCII; format=flowed

Hi Eli

it's hard to say without looking at an image. Can you upload a subject and 
point us at a spot you think is incorrect? And do you really think the 
thickness should be 0 - there is no gray matter left at all? That seems 
unlikely....

cheers
Bruce