looks like it is only different in the first or second decimal place, is that right? If so, then it is acceptable.

On 8/22/2024 4:11 PM, Sneha Pandya wrote:

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Dear team,

 

A] I am running mri_gtmpvc on our data and need to extract stats data that is in the similar format as gtm.stats.dat file from non-pvc corrected PET data, in the sense getting mean regional uptake from non-pvc PET data alongside region names, volumes, var, etc information using ROIs from gtmseg.

 

mri_gtmpvc command (turned off PVC):

mri_gtmpvc --i PET.nii.gz --reg PET_to_nu.reg.lta --seg ${ FreeSurferDir }/mri/gtmseg.mgz --default-seg-merge --auto-mask ${FWHM} .01 --psf 0 --no-tfe --no-rescale --save-input --o nopvcoutput

 

I tried this with following approaches as suggested in the forum:

1] mri_convert nopvc.nii.gz --ascii nopvc_1.stats.dat

2] mri_segstats --i input.nii.gz --seg aux/seg.nii.gz --ctab aux/seg.ctab --excludeid 0 --sum nopvc_2.stats.dat

 

On comparing mean uptake between nopvc_1.stats.dat and nopvc_2.stats.dat, I see that values are similar but not same. Is this expected?

 

Head of nopvc_1.stats.dat:

54832.960938

65543.554688

59080.023438

75662.140625

47840.519531

61120.222656

66590.773438

69356.742188

58847.007812

65715.578125

 

Head of nopvc_2.stats.dat:

Index

SegId

NVoxels

Volume_mm3

StructName

Mean

StdDev

Min

Max

Range

1

2

106905

223886.7

Left-Cerebral-White-Matter

54832.95

8839.049

15160.92

96317.77

81156.85

2

7

7723

16174

Left-Cerebellum-White-Matter

65543.57

10289.78

26951.39

90987.36

64035.97

3

8

24806

51950.2

Left-Cerebellum-Cortex

59079.91

14349.17

13388.75

107889.7

94500.95

4

10

3427

7177

Left-Thalamus

75662.06

13054.39

33599.36

105854.3

72254.89

5

11

1813

3796.9

Left-Caudate

47840.52

10624.56

19515.38

88224.69

68709.31

6

12

2280

4774.9

Left-Putamen

61120.21

8453.317

43591.13

83701.97

40110.84

7

13

976

2044

Left-Pallidum

66590.77

5816.431

50056.58

83431.62

33375.04

8

16

6686

14002.2

Brain-Stem

69356.77

16951.96

20199.62

115301.7

95102.11

 

 

B] Also, when we turn off PVC with “--psf 0 --no-tfe” flags, SGTM is still performed right whose regional data is saved in gtm.stats.dat file? If we perform RBV PVC does it in addition affect in anyway SGTM outputs (i.e gtm.stats.dat)?

 

C] Is there a way to erode only reference region in the mri_gtmpvc command both when PVC is performed (SGTM or RBV) and with no PVC? If not, is there a way to do so after running mri_gtmpvc to rescale PVC’ed and non-PVC’ed uptake with eroded cerebellum derived from gtmseg? I have extracted eroded GM cerebellum from gtmseg using mri_binarize and then planning to use that eroded GM cerebellum mask to rescale PVC’ed/non-PVC’ed regional uptake, not sure if it is the right approach.

 

mri_binarize command:

mri_binarize --i ${FreeSurferDir}/mri/gtmseg.mgz --o CerebellumGrayMatterMaskEroded_gtmseg.mgz --match 8 47 --erode 2

 

Thank you,

Sneha

 


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