Dear Experts:

 

I am very new to freesurfer glmfit and this post may seem dumb. I wanted to find the correlation between Cth and Education for each of HC and RRMS group regressing out the effect of gender and (demeaned) age. My fsgd file is something like below. 

 

GroupDescriptorFile       1                                             

Title       Group-Edu-Correlation                                 

MeasurementName       thickness                                            

Class      FemaleHC                                          

Class      FemaleRRMS                                                                                                    

Class      MaleHC                               

Class      MaleRRMS                                                                                         

Variables             Age        Education                           

Input     1              FemaleRRMS     -7.97      0.243

Input     2              MaleRRMS          -2.97      -1.300

Input     3              FemaleHC           -12.97    -0.914

Input     5              Male HC               4.03        -1.686

…………………..

I used DODS method.

For HC, I set the correlation matrix as: 0  0  0  0  0  0  0  0  0.5  0  0.5  0

And for RRMS, I set the matrix as:  0  0  0  0  0  0  0  0  0  0.5  0  0.5

 

  1. I am wondering, if my DODS contrasts are correct.
  2. To get better DOF, should I create two different FSGD file for each group (i.e. one for HC and one for RRMS)?
  3. If I create two different FSGD file for each group then can I use DOSS method and use the contrast: 0 0 0 1 ?

 

Thanks,

Anwar

 

 

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