Hi,

 

I have a question:

 

My design is 2 groups (HC and Patients in that respective order) and 2 nuisance factors (age and eTIV). When I look at the average volume difference between the 2 groups, I get blue and red clusters. I presume the color coding is where each group is greater than the other (Blue = Patients > HC and Red = HC > Patients).

 

Then, I processed to extract individual values from each cluster in order to plot them. When I extract data from the blue clusters and plot them, the two groups show no difference in thickness at all, whereas when I look at volume, HC show more than patients in blue clusters (see attached figure). I would assume that both figures would show patients > HC based on the negative statistic.

 

Am I interpreting the colors wrong? Or am I doing something wrong?

 

These are my steps 1) After applying montecarlo correction, I drew my ROIs to extract the data from; 2) map it onto every single subject; and then 3) used mris_anatomical_stats to extract the data from each subject.  

 

Any suggestions are welcome.

 

Best,

Omar

 

Jose O. Maximo, Ph.D. | Postdoctoral Fellow

Department of Psychiatry & Behavioral Neurobiology

UAB School of Medicine

University of Alabama at Birmingham

Cell Phone: (619) 252-3492

Email: jomaximo@uabmc.edu