Thanks, Doug.

I'm still a little unclear about how to set up a timeseries regressor (120 timepoints) in the design matrix while also specifying the # of subjects (500). Would the design matrix be a 500x120 or 120x500?

I should mention that my ultimate goal is to find a statistically sig. threshold for a cortical fcMRI map with 500 subjects. Traditional correction for multiple comparisons, like Bonferroni and FDR, are not sufficient. So I'd now like to find a cluster size-based correction threshold using mri_glm-sim. Hence, my desire to create the cortical fcMRI map using mri_glmfit, so I can get the files needed for mri_glm-sim. Is this an okay approach, or is there a better way to do this?

Thank you so much,
Eun Young



On Wed, May 4, 2016 at 3:15 PM, Douglas N Greve <greve@nmr.mgh.harvard.edu> wrote:
We don't usually use mri_glmfit for this kind of thing. If you want to
do it this way, then you cannot use an FSGD file. Instead, create a
design matrix with the seed time course then pass that to mri_glmfit
with the --X option (and no --fsgd option).

On 05/04/2016 10:17 AM, Eun Young Choi wrote:
>
> Hi all,
>
> I'd like to run a resting-state fcMRI analysis within the GLM
> (mri_glmfit), but I'm not completely sure how to set this up in the
> FSGD file. I've seen the online tutorial of age vs cortical thickness,
> but I'm not sure how to specify a regressor with a timeseries. Does
> anyone have an example of an FSGD file for this?
>
> Thanks!
> Eun Young
>
>
>
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Eun Young Choi, PhD

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