Hi Doug et al.,

It appears I've encountered this problem once before:

https://mail.nmr.mgh.harvard.edu/pipermail//freesurfer/2016-February/043647.html

Unfortunately there is no record of any resolution (if there was one) in the original thread, and I have no recollection of what the outcome was. Where the thread did leave off was a request for the Xtmp.mat file, so I will include the Xtmp.mat file from the analysis that worked (GoodXtmp.mat) and the one that failed (BadXtmp.mat).

The error message:

Creating Design Matrix
 ... creation time =  0.019 sec
DoMCFit = 1
ntptot = 2592, nX = 81, DOF = 2511
Saving X matrix to /home/chris/SEM/FS_0231/bold/FAM.self.sm4.down.rh/Xtmp.mat
Error using svd
Input to SVD must not contain NaN or Inf.
Error in cond (line 35)
    s = svd(A);
Error in fast_selxavg3 (line 279)
  XCond = cond(XtX);

Curiously, unless something was overlooked, the same analysis was carried out on another dataset that went through the same preprocessing steps without incident.

The Xn matrix in BadXtmp.mat contains 3 columns of NaN (:,[7,8,9]), but without knowing how those values are calculated, I can't take a principled stab at fixing the problem.

Thanks for your help,

Chris