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Hi Douglas, 

Here is the command line: 
mri_glmfit \
  --y rh.thickness-rate.MyStudy.10.mgh \
  --fsgd FSGD/MyStudy.fsgd dods\
  --C Contrasts/Case-Control_age_gender_race_etiv.mtx\
  --surf fsaverage rh \
  --cortex \
  --glmdir rh.thickness-rate.MyStudy.10.mgh_age_gender_race_etiv.glmdir \
  --eres-save

Also error message in terminal:
gdfRead(): reading FSGD/MyStudy.fsgd
WARNING: variable 1 is "Gender" which is often a discrete factor
  The proper way to handle discrete factors is to create classes.
ERROR: gdfReadV1: Format Error: Input line 1, subjid = sub001_base
 Variable 2 has character string Female
 Variables should be continuous numbers
FSGDF Format Error: file = FSGD/MyStudy.fsgd, tag=Input

Also attached FSGD file below. 
Thank you so much for the help!

Best, 
Zeng




On Wed, Nov 10, 2021 at 5:41 PM Douglas N. Greve <dgreve@mgh.harvard.edu> wrote:
please send your command line and full terminal output as well as the fsgd file

On 11/10/2021 5:12 PM, Zeng, Qi wrote:

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Hi Freesurfer experts, 

Here, I want to design a simple group comparison (two levels: Case vs. Control) and also count for 4 covariates (two continuous and two categoricals). However, the GLM model cannot recognize my discrete variables. What do you suggest to change?
>> FSDG file:
GroupDescriptorFile 1
Title MyStudy
Class Control
Class Case
Variables age gender race  eTIV
Input sub001_base Control 85 Female White 1350519
Contrast:
>> Design matrix for Case-Control and regress out the effect of age, gender, race, and eTIV. 
-1 1 0 0 0 0 0 0 0 0 

Best, 
Zeng




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Ph.D. candidate 
Icahn School of Medicine at Mount Sinai