Dear FreeSurfers,

 

I have been processing a group of subjects, firstly using Freesurfer V5.1.0 or V5.3.0, then V5.3.0 after making some editing on WM and pial surface, using the <recon-all> command, without the <-no-isrunning> option.

 

I have below message at the beginning of the recon-all after editing:

 

INFO: FreeSurfer build stamps do not match

Subject Stamp: freesurfer-Linux-centos4_x86_64-stable-pub-v5.3.0

Current Stamp: freesurfer-Linux-centos6_x86_64-stable-pub-v5.3.0

 

INFO: SUBJECTS_DIR is /home/zixuan/Work/FS/RE_EDIT

Actual

FREESURFER_HOME /usr/share/freesurfer

-rw-r--r--. 1

zixuan users 957929 Dec 20 16:52 /home/zixuan/Work/FS/RE_EDIT/D3358/scripts/recon-all.log

Linux NIL.Melbourne 2.6.32-358.23.2.el6.x86_64 #1 SMP Wed Oct 16 18:37:12 UTC 2013 x86_64 x86_64 x86_64 GNU/Linux

 

INFO: current FREESURFER_HOME does not match that of previous processing.   

Current: /usr/share/freesurfer   

Previous: /share/apps/freesurfer/5.3.0

#--------------------------------------------

#@#

Mask BFS Wed Apr  2 17:11:43 EST 2014

/home/zixuan/Work/FS/RE_EDIT/D3358/mri

mri_mask -T 5 brain.mgz brainmask.mgz brain.finalsurfs.mgz

 

However all subjects have been finished without error, which is not the case as what you have discussed in the mail archive.

 

recon-all -s <subjID> finished without error at Mon Mar 24 03:38:36 EST 2014

 

The problem is, I found the cortical thickness in regions that I didn’t edit not consistent before and after re-processing, with about 2-10% differences. For some subjects, I have only edited minor pial surface (e.g. entorhinal cortex only), yet it seems that all values have been affected.

 

My question is

1), shall I consider my results valid, despite of the “dismatch” thing? Is there any other factors other than editing will affect the final value?

 

2), I have about 30 subjects processed with V5.1.0, (atrophic brain +++ with heavy editing – extreme time consuming), yet I still found some pial to edit this time, and processed them with V5.3.0. Shall I consider the values valid provided the message “without error”, despite the different FreeSurfer versions?

 

Apologies for cross posting, I didn’t found any cases similar to mine in the mail archive.

 

Many thanks and kind regards,

Zixuan

 

 

--

Zixuan YANG

 

Ph.D candidate
Centre for Healthy Brain Ageing (CHeBA)

School of Psychiatry, UNSW Medicine

NPI, Euroa Centre, Barker Street, Randwick

NSW  2031  AUSTRALIA

T: +61 (2) 9385 0427    

W: www.cheba.unsw.edu.au

E: z.yang@student.unsw.edu.au

______________     

Mailing address:  

University of New South Wales  

Randwick Campus, Building R1f    

22-32 King Street, Randwick NSW 2031

Australia