Hi Freesurfer experts,

    I'm very sorry to bother you, but I am very confused with the
    following questions:

    My experimental design includes two discrete factors:
    with three levels (d,m,h); gender (f, m), and two Nvariables

    So I can get 6 classes: df, dm,mf, mm,hf,hm.

     I want to perform the difference between any of the classes
    leves analysis with regressing out the effect of gender and two
    Nvariables, but I don't know the rules for setting the contrasts for
    the F-test.  The contrast matrix I used is:

    1 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
    0 0 0 1 -1 0 0 0 0 0 0 0 0 0 0 0 0 0
    1 0 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
    0 0 0 1 0 -1 0 0 0 0 0 0 0 0 0 0 0 0
    My orders are as follows£º
    mris_preproc --fsgd glmteach.fsgd --target fsaverage --hemi lh --meas area --out lh_teach.mgh
    mris_preproc --fsgd glmteach.fsgd --target fsaverage --hemi rh --meas area --out rh_teach.mgh

    mri_glmdir --y lh_teach.mgh --fsgd glmteach.fsgd --C glmteach.mtx --glmdir group.area_sm.lh --fwhm 10 --surface fsaverage lh --eres-save

    mri_glmdir --y rh_teach.mgh --fsgd glmteach.fsgd --C glmteach.mtx --glmdir group.area_sm.rh --fwhm 10 --surface fsaverage rh --eres-save

    mri_glmdir-sim --glmdir group.area_sm.lh --2spaces --cwp 0.05 --perm 100 1.3 abs
    mri_glmdir-sim --glmdir group.area_sm.rh --2spaces --cwp 0.05 --perm 100 1.3 abs

       But there is no region of interest after running£¬
       Can I change the correction method or did I use it wrong


        Any help will be very appreciated.

        Best wishes,