Hi Doug,

Thanks for getting back to me so quickly. Just to confirm, I can proceed to use the mri_glmfit analysis as shown on the group level tutorial? 

I'm not sure I can do the paired analysis since my subjects in one group are not matched with those from the other and one group has more participants than the other. I will however use the the link you gave me to compute the difference within one of my groups.

Best,

Arsenije