Hello all,

I use Freesurfer-Samseg for MS lesion segmentation(cross-sectional).

I use the T1 and Flair for this. (just these are inputs) I registered flair and t1 to DIR for every patient. (My manual lesion masks are on DIR imaging.) I controlled the registrations, these are true.

I created a binary lesion mask using threshold 0.05. (mri_binarize --i /data/projects/MS_MRI/posteriors/Lesions.mgz --o /data/projects/MS_MR/binarize/lesion_binary.mgz --min 0.05)

I checked the dice score with ground truth values with python.

threshold 0.05= dice 0,2 of the dataset

Do you have any recommendations to increase the dice?

# cvs_version 7.2.0

# sysname Linux

# machine x86_64

Best regards