It will impact it some as it changes the talairach reg. See https://surfer.nmr.mgh.harvard.edu/fswiki/ReleaseNotes

On 1/31/2022 2:59 PM, Ritobrato Datta wrote:

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Hi All,

I have inherited some T1 data that are defaced. 

If I run the defaced images through freesurfer, will that impact the eICV calculations ?

Please let me know. 

Many thanks

Ri

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