Hi Donna,

In that same paper we also comment on the differences between expansion/contraction and absolute areal measurements assessed at each face of the surface (i.e., facewise), which can, after interpolation, be converted to vertexwise to facilitate analysis using current tools (e.g., mri_glmfit or qdec), without loss of areal quantities.

All the best,

Anderson


On 11 October 2014 04:05, Donna Dierker <donna@brainvis.wustl.edu> wrote:
Hi Emma,

I might not be the only one who is unsure what you mean by a vertex-wise cortical surface area measure.  Do you mean something like what is illustrated in figures 2 and 3 here:

http://www.pnas.org/content/107/29/13135.figures-only

… which is similar, but not identical to the local gyrification index?

If so, would you use this measure on surfaces before or after registration to a target atlas?

Donna


On Oct 10, 2014, at 4:19 PM, Emma Thompson <voneconomos@gmail.com> wrote:

> Dear Freesurfers,
> I recently heard that there are several disadvantages to using a measure of cortical surface area in Freesurfer, specifically due to conducting a vertex-wise analysis. Can someone help me understand why a measure of surface area using this approach might be flawed? Thanks!



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