Hi Doug,

I ran voxel based analysis in FSL to check the differnce in PET signal between two groups. The results are totally differnt than surface based analysis in Freesurfer.  I this real or I am doing something wrong? I tried to do the same but using FA maps and also I got totally differnt results.

 

I have special interest in understanding why these two methods leads to differnt results?!

I have read this refernce http://cds.ismrm.org/protected/11MProceedings/files/ISMRM2011-8410.pdf and actually I was unable to reach the point that can explain this differnce in th results. I highly appreciate if you clarify that to me.