Hi Priti,

Thanks for your help. I took another look at the original diffusion and anatomical images. The anatomical looks OK, but in the diffusion image a posterior region of the brain appears cutoff and when I view the image in freeview there is a green box in the lower left hand corner that I've never seen before (I've attached a shot). I'm new to Freesurfer so I would appreciate any help you may have.

Thanks again,

Kiely

On Tue, Jan 24, 2012 at 1:21 PM, Priti Srinivasan <rspriti@nmr.mgh.harvard.edu> wrote:
Hi Kiely,

I had a similar experience with one of my subjects, but I realized that
the original diffusion image had a lot of signal loss in various regions
and hence the subsequent registration steps failed.

It can happen when either intra-subject or inter-subject registration
fails. I would inspect the original diffusion image (dmri/dwi_orig.nii.gz)
and the original anatomical (dlabel/anat_brain_mask.nii.gz) to see if they
have any problems (signal loss etc) which could lead to failures in
registration as a first step.

If both your diffusion and anatomical are both good, then I'd try to do
flirt seperately to see if you get the same results as the one produced by
tracula.

Hope this is helpful,

Priti





> Hi Anastasia,
>
> Sorry for my slow reply. I am working with data that I only have access
to
> intermittently. We were able to fix the problem by deleting the original
files from the folder and re-running the bedpost step. The old files
must
> have been interfering in some way.
>
> I am hoping you can help me with a different problem I ran into. For
several of our subjects, each pathway reconstruction fails and I get an
error like the following for all 18 tracts:
>
> Processing pathway 16 of 18...
> Initializing MCMC
> INFO: Path from initial control points is not entirely in mask
> INFO: or is self-intersecting
> INFO: Attemping to perturb control points
> ERROR: Path from initial control points is not entirely in mask
> ERROR: or is self-intersecting
> ERROR: Initialization failed
> ERROR: Pathway reconstruction failed
> Done in 0.216 sec.
>
> I am able to view the FA image in native space, but when I attempt to
view
> the FLIRT-registered FA image it's completely dark. Is there any reason you
> can think of that this may be happening?
>
> Thanks in advance,
>
> Kiely
>
>
> On Fri, Dec 23, 2011 at 2:42 PM, Anastasia Yendiki <
> ayendiki@nmr.mgh.harvard.edu> wrote:
>
>> Hi Kiely - It's strange that bepostx would create ph2samples and not
ph1samples. These are the orientation angles for the 2 anisotropic
compartments, so if there's a 2nd there should be a 1st. Have you asked
about it on the FSL list?
>> a.y
>> On Thu, 22 Dec 2011, Kiely Donnelly wrote:
>>  Hi Everyone --
>>> I've been having difficulty getting Tracula to run smoothly on our
cluster. Similar to others on the listserv, the bedpost step
>>> was not creating the necessary files causing an error during the -path
step. Based on previous posts, I ran bedpostx on the dmri
>>> directory. This initially seemed to work (I no longer received the
message "1 slice processed" over and over), but for some reason the
merged_ph1samples.nii.gz file is still not being created and I
continue to run into an error when I run -path. It does create a
merged_ph2samples.nii.gz output file.
>>> Any help would be greatly appreciated.
>>> Thanks,
>>> Kiely
>> The information in this e-mail is intended only for the person to whom it
>> is
>> addressed. If you believe this e-mail was sent to you in error and the
e-mail
>> contains patient information, please contact the Partners Compliance
HelpLine at
>> http://www.partners.org/**complianceline<http://www.partners.org/complianceline>.
If the e-mail was sent to you in error
>> but does not contain patient information, please contact the sender and
properly
>> dispose of the e-mail.
>
>
> --
> Kiely M. Donnelly, M.A.
> Doctoral Candidate, Clinical Neuropsychology
> University of Cincinnati
> _______________________________________________
> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer






--
Kiely M. Donnelly, M.A.
Doctoral Candidate, Clinical Neuropsychology
University of Cincinnati