Hi,all:

I was using mri_glmfit-sim for multiple correction,but I'm wondering if --3paces could influence the correction result.

From the website I saw the explanation below:

mri_glmfit-sim --glmdir my-glm.wls --cache 3 pos --cwpvalthresh .0166

Using a cluster-wise p-value threshold of p < .0166 corrects across all three spaces for p<.05 (ie, .0166 = .05/3). This corrections for a whole brain (ie, lh, rh, and subcortical) analysis.

Also,from the help document I saw:

--3spaces : additional Bonferroni correction across 3 spaces (eg, lh, rh, mni305)

So, I'm wondering if the command:

' mri_glmfit-sim --glmdir my-glm.wls --cache 3 pos --cwpvalthresh .0166 '

same with the command:

' mri_glmfit-sim --glmdir my-glm.wls --cache 3 pos --cwpvalthresh .0166 --3spaces '

or same with the command:

' mri_glmfit-sim --glmdir my-glm.wls --cache 3 pos --cwpvalthresh .05 --3spaces '.

If there is anyone know this question clearly, please reply me.

Many thanks.

Best regards.

Han